SCHEMBL472544

SCHEMBL472544

O=[N+]([O-])c1ccc2c(c1)Cc1ccccc1[S+]2[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.45
▸ KMT2A Q03164 4/20 0.45
▸ MAPT P10636 3/20 0.45
▸ LMNA P02545 3/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ TLR9 Q9NR96 1/20 0.45
▸ CYP1A2 P05177 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ TSHR P16473 1/20 0.40
▸ TDP2 O95551 1/20 0.40
▸ PARP1 P09874 2/20 0.39
▸ ADRA2A P08913 1/20 0.39
▸ PNMT P11086 1/20 0.39
▸ PTPRC P08575 2/20 0.38
▸ ACHE P22303 2/20 0.38
▸ BCHE P06276 1/20 0.38
▸ CES1 P23141 1/20 0.38
▸ S100A4 P26447 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8086579 0.91 MEN1 (0.45) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL11160025 0.83 ACHE (0.46) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL11658906 0.80 MAPT (0.39) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL10800979 0.80 ACHE (0.42) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL11304593 0.80 TDP1 (0.41) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL11634337 0.79 TDP1 (0.46) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL11664480 0.78 TDP1 (0.42) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL9160477 0.77 MAOA (0.39) MAPTLMNARAB9ACYP1A2HSD17B10
SCHEMBL36333 0.77 MAOA (0.39) MAPTLMNARAB9ACYP1A2HSD17B10
SCHEMBL10476775 0.77 MAOA (0.39) MAPTLMNARAB9ACYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367745-B2 Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis GC CORPORATION (JP) 2013-02-05 — — US claimed
US-7678843-B2 Dental restorative material composition GC CORPORATION (JP) 2010-03-16 — — US claimed
US-5770638-A CONSISTS OF TETRAHYDROFURFURYL METHACRYLATE, ONE OR MORE METHACRYLATE HAVING ATLEAST ONE DOUBLE BOND SELECTED FROM DI-2-METHACRYLOXYETHYL-2,2-4-TRIMETHYLHEXAMETHYLENE DICARBAMATE AND OTHER ACRYLATED CARBAMATE AND PHOTOINITIATORS GC CORPORATION (JP) 1998-06-23 — — US claimed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 — — EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 — — US disclosed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 — — EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 — — EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 — — US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 — — US disclosed
US-12497476-B2 Antibacterial polymer particles, composition, and article GC CORPORATION (JP) 2025-12-16 — — US disclosed
EP-4652982-A1 DENTAL RESTORATION MATERIAL COMPOSITION GC R&D Corporation (JP) 2025-11-26 — — EP disclosed
US-5364890-A (meth)acrylate and a carbodiimide GC CORPORATION (JP) 1994-11-15 — — US disclosed
US-5356951-A (Meth)acrylate monomer; composite filler; glass powder; fine particle filler; photoinitiator; surface smoothness; less shrinkage GC CORPORATION (JP) 1994-10-18 — — US disclosed
US-5290172-A Method for preparing a tooth surface for bonding GC CORPORATION (JP) 1994-03-01 — — US disclosed
US-5254604-A Light polymerizable resin compositions for the preparation of clasp patterns G-C TOSHI KOGYO CORPORATION (JP) 1993-10-19 — — US disclosed
US-5063255-A (Meth)acrylates G-C TOSHI KOGYO CORPORATION (JP) 1991-11-05 — — US disclosed
US-4843110-A BLEND CONTAINING A THIOXANTHONE PHOTOINITIATOR G-C DENTAL INDUSTRIAL CORPORATION (JP) 1989-06-27 — — US disclosed
US-4544467-A PHOSPHOROUS-CONTAINING UNSATURATED MONOMER , SULFUR COMPOUND AND PHOTOINITIATOR; BONDING STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-01 — — US disclosed
EP-0132318-A1 Light-curable dentin and enamel adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-30 — — EP disclosed
US-4379039-A Ultraviolet curable resin composition TOYO BOSEKI KABUSHIKI KAISH (JP) 1983-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO MEN1 1288/4885KMT2A 3602/4885MAPT 3169/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 MEN1 1762/4885KMT2A 2369/4885MAPT 619/4885
US-12497476-B2 Antibacterial polymer particles, composition, and article PCNA, PARG, PUF60 MEN1 3446/4885KMT2A 3848/4885MAPT 2383/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 MEN1 4117/4885KMT2A 2591/4885MAPT 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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