SCHEMBL11635334

SCHEMBL11635334

CC(C)(C)NC(=O)ON=C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RAB9A P51151 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
KDM4E B2RXH2 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11634041 0.75 MAPK1 (0.48) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL11638240 0.74 MEN1 (0.48) KMT2AMEN1MAPK1ALDH1A1
SCHEMBL11632039 0.72 RAB9A (0.63) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL11637095 0.68 KMT2A (0.53) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL4252918 0.68 KMT2A (1.00) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL14572071 0.66 ALDH1A1 (0.54) KMT2AMEN1MAPK1ALDH1A1SMN1; SMN2
SCHEMBL4464244 0.62 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL27961248 0.62 ALDH1A1 (0.32) ALDH1A1LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL27961251 0.61 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL4877698 0.61 ALDH1A1 (1.00) KMT2AMEN1MAPK1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4104251-A POLYMER STABILIZERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed