SCHEMBL11635641

SCHEMBL11635641

Cc1c(Br)c(Br)nn1CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
GAA P10253 1/20 0.53
LMNA P02545 2/20 0.46
APAF1 O14727 1/20 0.44
HTT P42858 1/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 3/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3585241 0.85 ALDH1A1 (0.67) ALDH1A1GAALMNAAPAF1HTT
Ethane SCHEMBL11828584 0.83 ALDH1A1 (0.65) ALDH1A1GAALMNAAPAF1HTT
Ethane SCHEMBL11629623 0.81 LMNA (0.46) ALDH1A1GAALMNAAPAF1HTT
SCHEMBL11831505 0.80 RAB9A (0.43) ALDH1A1LMNAAPAF1HTTMAPT
SCHEMBL11832157 0.80 NPSR1 (0.43) ALDH1A1GAALMNAAPAF1HTT
SCHEMBL11628045 0.80 LMNA (0.44) ALDH1A1GAALMNAHTT
SCHEMBL11830102 0.79 MAPK1 (0.49) ALDH1A1GAALMNAHTTMAPT
SCHEMBL18554457 0.79 GAA (0.51) ALDH1A1GAALMNAAPAF1HTT
Methane SCHEMBL11629915 0.78 LMNA (0.43) ALDH1A1GAALMNAHTT
Butane SCHEMBL11630643 0.78 LMNA (0.43) ALDH1A1GAALMNAAPAF1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4084955-A 1-CARBOXYALKYL-DI- AND TRIHALOPYRAZOLES, HERBICIDES THE UPJOHN COMPANY (US) 1978-04-18 US claimed
US-3957480-A HERBICIDES THE UPJOHN COMPANY (US) 1976-05-18 US disclosed