Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.69 |
| ▸ | F2R | P25116 | 1/20 | 0.64 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787204 | 0.85 | TMPRSS4 (0.76) | TMPRSS4GPR27P2RX1P2RX4P2RX7 | |
| SCHEMBL9967909 | 0.83 | HSPD1 (0.67) | GPR27TP53PPARGP2RX1HSPD1 | |
| SCHEMBL10612716 | 0.83 | TMPRSS4 (0.73) | TMPRSS4GPR27TP53PPARGP2RX1 | |
| SCHEMBL538439 | 0.82 | TMPRSS4 (1.00) | TMPRSS4TP53P2RX1P2RX4P2RX7 | |
| SCHEMBL23003264 | 0.81 | TMPRSS4 (0.69) | TMPRSS4GPR27P2RX1P2RX4P2RX7 | |
| SCHEMBL12319804 | 0.81 | TMPRSS4 (0.69) | TMPRSS4GPR27P2RX1P2RX4P2RX7 | |
| SCHEMBL2227567 | 0.80 | MEN1 (0.76) | TMPRSS4GPR27TP53MEN1KMT2A | |
| SCHEMBL3325727 | 0.79 | TMPRSS4 (0.68) | TMPRSS4GPR27P2RX1P2RX4P2RX7 | |
| SCHEMBL882734 | 0.79 | KMT2A (0.80) | F2RTP53HSPD1HSPE1MEN1 | |
| SCHEMBL7172686 | 0.79 | TMPRSS4 (0.77) | TMPRSS4GPR27TP53P2RX1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |