Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | F12 | P00748 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.57 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343477 | 0.85 | TMPRSS4 (0.67) | HSPD1HSPE1RAB9APOLBNPC1 | |
| SCHEMBL330113 | 0.85 | TMPRSS4 (0.67) | HSPD1HSPE1RAB9APOLBNPC1 | |
| SCHEMBL23825504 | 0.85 | SORT1 (0.74) | HSPD1HSPE1F12AVPR2GPR27 | |
| SCHEMBL29980628 | 0.85 | SORT1 (0.74) | HSPD1HSPE1F12AVPR2GPR27 | |
| SCHEMBL10289025 | 0.83 | POLB (0.61) | HSPD1HSPE1MAPTRAB9APOLB | |
| SCHEMBL11636637 | 0.83 | TMPRSS4 (0.69) | HSPD1HSPE1MAPTRAB9ANPC1 | |
| SCHEMBL11575251 | 0.83 | ALDH1A1 (0.57) | HSPD1HSPE1MAPTRAB9APOLB | |
| Dibromsalan SCHEMBL29211119 | 0.82 | PLAU (0.66) | HSPD1HSPE1MAPTRAB9APOLB | |
| SCHEMBL338230 | 0.82 | HSPD1 (0.57) | HSPD1HSPE1MAPTRAB9APOLB | |
| SCHEMBL882734 | 0.82 | KMT2A (0.80) | HSPD1HSPE1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232455-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-08-20 | — | — | US | disclosed |
| US-20150232455-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-08-20 | — | — | US | disclosed |
| WO-2012083059-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232455-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | HSPD1 1014/4885HSPE1 730/4885MAPT 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.