Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796572 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL11637890 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL11635261 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL4266313 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL11635537 | 0.72 | PRSS1 (0.42) | ALDH1A1MAPTMAPK1TP53KMT2A | |
| SCHEMBL10891158 | 0.68 | KDM4E (0.64) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL19375695 | 0.68 | KDM4E (0.45) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL26750153 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL20626383 | 0.68 | TP53 (0.43) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL11241059 | 0.68 | BCL2L1 (0.37) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |