Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637262 | 0.87 | KDM4E (0.42) | ALDH1A1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL8604899 | 0.79 | L3MBTL1 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL4266313 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL8485321 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8483548 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL11373378 | 0.75 | KDM4E (0.49) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8087890 | 0.75 | KDM4E (0.59) | ALDH1A1KDM4EHPGDMAPK1GAA | |
| SCHEMBL11241059 | 0.73 | BCL2L1 (0.37) | ALDH1A1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL30982940 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL11637890 | 0.71 | KDM4E (0.59) | ALDH1A1KDM4EHPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777704-A1 | NAPHTHOLACTAM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006137-A1 | NAPHTHOLACTAM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-29 | — | — | WO | disclosed |