Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR6 | P46095 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163256 | 0.84 | GAA (1.00) | LMNAGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL16209962 | 0.81 | ALDH1A1 (1.00) | LMNAGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL11640504 | 0.81 | P2RX4 (0.58) | LMNAGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL10509926 | 0.73 | NOTUM (0.56) | LMNAGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL30865951 | 0.72 | ALOX5 (0.72) | GAAKMT2AALDH1A1POLBHPGD | |
| SCHEMBL12069952 | 0.72 | KMT2A (0.84) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL13836513 | 0.71 | ALOX5 (0.72) | GAAKMT2AALDH1A1POLBHPGD | |
| SCHEMBL5244645 | 0.71 | POLB (0.92) | LMNAGAAKMT2AALDH1A1MEN1 | |
| Ethylene SCHEMBL28911980 | 0.70 | EPHX1 (0.69) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6966315 | 0.69 | ALDH1A1 (0.69) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124583-A | 5-Substituted derivatives of 5H-dibenz (b,f)-azepine and method for obtaining the same | DSO "PHARMACHIM" (BG) | 1978-11-07 | — | — | US | disclosed |