Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.85 |
| ▸ | MAPT | P10636 | 6/20 | 0.85 |
| ▸ | MEN1 | O00255 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16209962 | 0.92 | ALDH1A1 (1.00) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11637641 | 0.84 | LMNA (0.72) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL12401341 | 0.82 | ALDH1A1 (0.72) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2163031 | 0.78 | LMNA (0.63) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2162974 | 0.78 | LMNA (0.63) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL5783412 | 0.77 | HPGD (1.00) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL31556814 | 0.77 | HPGD (1.00) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5244645 | 0.76 | POLB (0.92) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2163718 | 0.75 | GAA (0.59) | GAALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL159415 | 0.74 | SIGMAR1 (0.63) | GAALMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985763-B2 | using an thiourea compound or carbonyl thiourea compound; therapy for drug resistant infections | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-07-26 | — | — | US | disclosed |
| US-7985763-B2 | using an thiourea compound or carbonyl thiourea compound; therapy for drug resistant infections | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-07-26 | — | — | US | disclosed |
| US-7985763-B2 | using an thiourea compound or carbonyl thiourea compound; therapy for drug resistant infections | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-07-26 | — | — | US | disclosed |
| WO-2008124300-A1 | HEPATITIS C VIRUS INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-10-16 | — | — | WO | disclosed |
| US-20080255189-A1 | HEPATITIS C VIRUS INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-10-16 | — | — | US | disclosed |
| US-20080255189-A1 | HEPATITIS C VIRUS INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-10-16 | — | — | US | disclosed |
| US-20080255189-A1 | HEPATITIS C VIRUS INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255189-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, ZC3HAV1, ZC3HAV1L | GAA 1481/4885LMNA 1064/4885ALDH1A1 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.