Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685398 | 0.90 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL5955265 | 0.89 | MEN1 (0.54) | HTTKMT2AMEN1CTSGCMA1 | |
| SCHEMBL11072116 | 0.84 | KMT2A (0.49) | HTTKMT2AMEN1CTSGCMA1 | |
| SCHEMBL9724603 | 0.83 | OPRK1 (0.52) | HTTKMT2AMEN1GAACYP3A4 | |
| SCHEMBL5955129 | 0.81 | PLCG1 (0.55) | KMT2AMEN1CTSGCMA1NPC1 | |
| SCHEMBL5955275 | 0.81 | KMT2A (0.56) | KMT2AMEN1CTSGNPC1RAB9A | |
| SCHEMBL5955047 | 0.81 | KMT2A (0.56) | KMT2AMEN1CTSGNPC1RAB9A | |
| SCHEMBL11638136 | 0.81 | NPC1 (0.56) | KMT2AMEN1CTSGCMA1NPC1 | |
| SCHEMBL11071726 | 0.80 | CTSG (0.51) | KMT2AMEN1CTSGCMA1NPC1 | |
| SCHEMBL11147745 | 0.79 | DUSP22 (0.47) | KMT2AMEN1CTSGCMA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473393-A | INSECTICIDES, MITICIDES, NEMATOCIDES, FUNGICIDES, AND HERBICIDE | BUFFALO COLOR CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |