Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634917 | 0.84 | DRD2 (0.38) | DRD2DRD3DRD4FFAR2PIK3CA | |
| SCHEMBL11634425 | 0.82 | DRD2 (0.41) | DRD2DRD3DRD4PIK3CAMTOR | |
| SCHEMBL12235941 | 0.79 | FFAR2 (0.38) | DRD2DRD3DRD4FFAR2KMT2A | |
| SCHEMBL15651256 | 0.79 | FFAR2 (0.38) | DRD2DRD3DRD4FFAR2KMT2A | |
| SCHEMBL11636528 | 0.79 | NNMT (0.39) | FFAR2MTORKMT2ANR3C2NR3C1 | |
| SCHEMBL24374635 | 0.77 | MTOR (0.54) | PIK3CAMTORRPTORMLST8 | |
| SCHEMBL11634928 | 0.77 | MTOR (0.54) | PIK3CAMTORRPTORMLST8 | |
| SCHEMBL30138377 | 0.74 | NR3C2 (0.46) | FFAR2PIK3CAMTORKMT2ANR3C2 | |
| SCHEMBL11636266 | 0.74 | NR3C2 (0.46) | FFAR2PIK3CAMTORKMT2ANR3C2 | |
| SCHEMBL20929742 | 0.74 | NR3C2 (0.46) | FFAR2PIK3CAMTORKMT2ANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104385-A | Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates | STERLING DRUG INC. (US) | 1978-08-01 | — | — | US | disclosed |