SCHEMBL11638545

SCHEMBL11638545

N=C(N=Cc1ccccc1C1CC1)NN

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL11635486 0.91 LMNA (0.32) HSD17B10
SCHEMBL11638550 0.76 GAA (0.42) L3MBTL1
SCHEMBL11638543 0.76 GAA (0.42) L3MBTL1
SCHEMBL11882884 0.74 GRIN2D (0.50)
SCHEMBL11875368 0.74 GRIN1 (0.49)
SCHEMBL4799723 0.73 HPGD (0.42) L3MBTL1HSD17B10
SCHEMBL28606288 0.73 HPGD (0.42) L3MBTL1HSD17B10
SCHEMBL1158588 0.70 LMNA (0.43) L3MBTL1
Maleic Acid SCHEMBL11635484 0.69 MAPT (0.40) L3MBTL1
SCHEMBL23607238 0.67 SMN1; SMN2 (0.37) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4109008-A SUBSTITUTED WITH AN AMIDINO AND A 1,3-DIMETHYL-2-OXO-BENZIMIDAZOL- 5-YL RADICAL HEXACHIMIE (FR) 1978-08-22 US disclosed