Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606288 | 1.00 | HPGD (0.42) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL21756096 | 0.78 | KDM4E (0.44) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL6779682 | 0.75 | FGF23 (0.57) | HPGDALDH1A1HTTTSHRFGF23 | |
| SCHEMBL11319128 | 0.74 | GRIN2D (0.40) | ALDH1A1FGF23LMNAL3MBTL1ESR2 | |
| SCHEMBL2161218 | 0.74 | KMT2A (0.40) | HPGDALDH1A1HTTL3MBTL1ESR2 | |
| SCHEMBL11638550 | 0.73 | GAA (0.42) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL11638545 | 0.73 | L3MBTL1 (0.33) | L3MBTL1HSD17B10 | |
| SCHEMBL11638543 | 0.73 | GAA (0.42) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL548147 | 0.72 | LMNA (0.52) | HPGDALDH1A1HTTTSHRLMNA | |
| SCHEMBL28958240 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411094-B2 | Method for the production of primary amines comprising a primary amino group which bound to an aliphatic or cycloaliphatic C-atom, and a cyclopropyl unit | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-12 | — | — | US | disclosed |
| US-20080064901-A1 | Method for the Production of Primary Amines Comprising a Primary Amino Group Which is Bound to an Aliphatic or Cycloaliphatic C-Atom, and a Cyclopropyl Unit | BASF (DE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064901-A1 | Method for the Production of Primary Amines Comprising a Primary Amino Group Which is Bound to an Aliphatic or Cycloaliphatic C-Atom, and a Cyclopropyl Unit | CYCS, DAO, MAOB | HPGD 2068/4885ALDH1A1 1991/4885HTT 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.