Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638585 | 1.00 | CTSK (0.60) | CTSKCTSSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11638205 | 0.89 | CTSK (0.47) | CTSKCTSSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11638376 | 0.88 | FAAH (0.51) | CTSKCTSSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27833801 | 0.87 | CTSK (0.62) | CTSKCTSSSMN1; SMN2GPR88S1PR3 | |
| SCHEMBL10240502 | 0.87 | CTSK (0.62) | CTSKCTSSSMN1; SMN2GPR88S1PR3 | |
| SCHEMBL16789067 | 0.86 | CTSK (0.54) | CTSKCTSSS1PR3 | |
| SCHEMBL25736775 | 0.86 | CTSK (0.58) | CTSKCTSSS1PR3 | |
| SCHEMBL11636318 | 0.84 | CTSK (0.46) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL16789064 | 0.84 | CTSK (0.56) | CTSKCTSSSMN1; SMN2LMNAS1PR3 | |
| SCHEMBL13934322 | 0.84 | CTSK (0.70) | CTSKCTSSLMNAGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108854-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
| US-3997584-A | Substituted glycines and intermediates thereof | SMITHKLINE CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3994954-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |