Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602019 | 0.86 | MAPK8 (0.46) | MAPTTP53LMNARXFP1PTGER4 | |
| SCHEMBL11635741 | 0.86 | NR1I2 (0.49) | MAPTTP53LMNAPTGER4 | |
| SCHEMBL11167513 | 0.86 | MAPT (0.57) | MAPTTP53LMNARXFP1 | |
| SCHEMBL11212672 | 0.85 | MAPT (0.50) | MAPTTP53LMNAPTGER1 | |
| SCHEMBL11164226 | 0.85 | POLB (0.51) | MAPTTP53LMNARXFP1 | |
| SCHEMBL11166830 | 0.83 | MAPT (0.43) | MAPTTP53LMNA | |
| Ciproquazone SCHEMBL287449 | 0.83 | CASR (0.58) | MAPTTP53LMNAPTGER4 | |
| SCHEMBL11636837 | 0.82 | MAPT (0.43) | MAPTTP53LMNARXFP1 | |
| SCHEMBL11166292 | 0.82 | PTGS2 (0.47) | MAPTTP53 | |
| SCHEMBL11159348 | 0.82 | PTGER4 (0.46) | MAPTTP53LMNAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |