Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 10/20 | 0.41 |
| ▸ | PARG | Q86W56 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870097 | 0.85 | PARG (0.38) | PTGS2CNR2PARGKCNH2 | |
| SCHEMBL11635741 | 0.84 | NR1I2 (0.49) | PTGS2MAPTTP53 | |
| SCHEMBL11858985 | 0.83 | GRIN1 (0.42) | PTGS2CNR2PARGKCNH2 | |
| SCHEMBL11861998 | 0.83 | ADORA2A (0.41) | CNR2PARGKCNH2 | |
| SCHEMBL11638587 | 0.82 | PLK1 (0.46) | MAPTTP53 | |
| SCHEMBL11602019 | 0.82 | MAPK8 (0.46) | MAPTTP53 | |
| SCHEMBL11167513 | 0.82 | MAPT (0.57) | MAPTTP53 | |
| SCHEMBL11166830 | 0.81 | MAPT (0.43) | MAPTTP53 | |
| Ciproquazone SCHEMBL287449 | 0.81 | CASR (0.58) | MAPTTP53 | |
| SCHEMBL11164226 | 0.81 | POLB (0.51) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387223-A | Process for preparing 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-07 | — | — | US | disclosed |
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |