Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383580 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EHIF1ACYP1A2CYP2D6 | |
| SCHEMBL11638740 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHIF1ALMNASMN1; SMN2 | |
| SCHEMBL11640971 | 0.82 | ALDH1A1 (0.73) | ALDH1A1KDM4ELMNAGABRPGABRD | |
| SCHEMBL11404065 | 0.80 | HIF1A (0.54) | ALDH1A1KDM4EHIF1ASMN1; SMN2MAPT | |
| SCHEMBL2384818 | 0.76 | HIF1A (0.51) | ALDH1A1KDM4EHIF1ASMN1; SMN2MAPT | |
| SCHEMBL2384823 | 0.76 | HIF1A (0.51) | ALDH1A1KDM4EHIF1ASMN1; SMN2MAPT | |
| SCHEMBL10679151 | 0.75 | KMT2A (0.60) | ALDH1A1KDM4EHIF1ACYP1A2CYP2D6 | |
| SCHEMBL10674889 | 0.74 | EGFR (0.61) | ALDH1A1KDM4EHIF1ALMNASMN1; SMN2 | |
| SCHEMBL2385559 | 0.74 | HIF1A (0.78) | HIF1A | |
| SCHEMBL12254526 | 0.74 | HIF1A (0.66) | HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |