Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.54 |
| ▸ | GABRE | P78334 | 1/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636684 | 0.85 | KDM4E (0.76) | ALDH1A1KDM4ELMNAALOX15MEN1 | |
| SCHEMBL30099678 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNANPC1ALOX15 | |
| SCHEMBL1061607 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNANPC1ALOX15 | |
| SCHEMBL11640249 | 0.84 | LMNA (0.80) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL11639579 | 0.83 | RECQL (0.72) | ALDH1A1KDM4ELMNANPC1GABRP | |
| SCHEMBL11639469 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNANPC1ALOX15 | |
| SCHEMBL11643253 | 0.80 | LMNA (0.61) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL1685954 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KDM4ELMNANPC1ALOX15 | |
| SCHEMBL11638740 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGABRPGABRD | |
| SCHEMBL11639723 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNANPC1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | claimed |
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |