Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642713 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4ERXFP1LMNAMEN1 | |
| SCHEMBL11641263 | 0.86 | RXFP1 (0.58) | ALDH1A1KDM4ERXFP1TSHRLMNA | |
| SCHEMBL11375460 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRLMNAMEN1 | |
| SCHEMBL11639469 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRLMNAHIF1A | |
| SCHEMBL11648831 | 0.83 | RXFP1 (0.46) | ALDH1A1KDM4ERXFP1TSHRLMNA | |
| SCHEMBL11639817 | 0.82 | RXFP1 (0.45) | ALDH1A1KDM4ERXFP1TSHRLMNA | |
| SCHEMBL11640971 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11642218 | 0.79 | LMNA (0.55) | ALDH1A1KDM4ERXFP1TSHRLMNA | |
| SCHEMBL11373100 | 0.79 | MEN1 (0.50) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL11643317 | 0.78 | LMNA (0.54) | ALDH1A1KDM4ERXFP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | claimed |
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |