Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 3/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638625 | 1.00 | SIGMAR1 (0.46) | SIGMAR1MAPTRXFP1FDPSLTB4R | |
| SCHEMBL4557580 | 0.98 | FDPS (0.46) | SIGMAR1MAPTRXFP1FDPSLTB4R | |
| SCHEMBL27782631 | 0.93 | POLB (0.45) | SIGMAR1FDPSKCNH2L3MBTL1POLB | |
| SCHEMBL114480 | 0.85 | TDP1 (0.43) | MAPTFDPSPOLB | |
| SCHEMBL11864517 | 0.84 | SIGMAR1 (0.44) | SIGMAR1MAPTRXFP1FDPSLTB4R | |
| SCHEMBL11640727 | 0.84 | IGF1R (0.46) | — | |
| SCHEMBL11637834 | 0.84 | IGF1R (0.46) | — | |
| SCHEMBL11639315 | 0.83 | TNNC1 (0.41) | FAAH | |
| SCHEMBL11641629 | 0.83 | TNNC1 (0.41) | POLB | |
| SCHEMBL11635584 | 0.83 | KCNH2 (0.46) | FDPSKCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125541-A | Aryl substituted ketones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125714-A | Aryl substituted cycloalkanones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |