Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642307 | 0.92 | SLC6A2 (0.55) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL11641938 | 0.84 | PGR (0.48) | SLC6A4SLC6A2OPRL1OPRM1LMNA | |
| SCHEMBL11637535 | 0.83 | PGR (0.49) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL11640983 | 0.81 | OPRL1 (0.53) | SLC6A4OPRL1OPRM1OPRK1LMNA | |
| SCHEMBL11640502 | 0.79 | LMNA (0.49) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL11643471 | 0.79 | L3MBTL1 (0.46) | SLC6A4SLC6A2OPRL1OPRM1LMNA | |
| SCHEMBL11640444 | 0.78 | CYP2D6 (0.58) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL16618696 | 0.78 | OPRL1 (0.51) | OPRL1OPRM1OPRK1LMNASMN1; SMN2 | |
| SCHEMBL11639729 | 0.77 | CYP2D6 (0.57) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL11642772 | 0.76 | OPRL1 (0.51) | OPRL1OPRM1OPRK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | claimed |
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | disclosed |
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |