Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460905 | 0.86 | GAA (0.46) | ALDH1A1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL11628340 | 0.75 | MAPT (0.39) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL7131453 | 0.69 | FFAR1 (0.43) | ALDH1A1KDM4ESMN1; SMN2CTSKFFAR1 | |
| SCHEMBL5282593 | 0.69 | GAA (0.46) | ALDH1A1LMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL11622951 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL12125729 | 0.65 | KMT2A (0.64) | ALDH1A1KMT2ALMNASMN1; SMN2TRPV4 | |
| SCHEMBL7581128 | 0.64 | POLB (0.74) | ALDH1A1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL436892 | 0.64 | EPHX2 (0.52) | FFAR1EPHX2 | |
| SCHEMBL11157410 | 0.64 | GAA (0.43) | ALDH1A1LMNAKDM4ESMN1; SMN2GAA | |
| SCHEMBL3260665 | 0.63 | HSP90AA1 (0.67) | KMT2ALMNATRPV4MEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117130-A | 6-PHENYL-1,2,4-TRIAZOLO(4,3-B)PYRIDAZINES | AMERICAN CYANAMID COMPANY (US) | 1978-09-26 | — | — | US | disclosed |