Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969624 | 0.85 | PDE4B (0.39) | PDE4BPDE4DALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL27668275 | 0.84 | PDE4B (0.38) | PDE4BPDE4DALDH1A1GAAKDM4E | |
| SCHEMBL6380564 | 0.83 | PDE4B (0.43) | PDE4BPDE4DALDH1A1GAATSHR | |
| SCHEMBL11454393 | 0.79 | DYRK1A (0.39) | PDE4BPDE4DALDH1A1GAATSHR | |
| SCHEMBL7399442 | 0.79 | PDE4B (0.40) | PDE4BPDE4DALDH1A1GAATSHR | |
| SCHEMBL4778825 | 0.76 | PDE4B (0.43) | PDE4BPDE4DALDH1A1GAATSHR | |
| SCHEMBL9024006 | 0.75 | PDE4B (0.43) | PDE4BPDE4DALDH1A1TSHRMAPK1 | |
| SCHEMBL9132120 | 0.74 | SMN1; SMN2 (0.47) | PDE4BPDE4DALDH1A1GAATSHR | |
| Hydrochloric Acid SCHEMBL14999713 | 0.74 | PDE4B (0.42) | PDE4BPDE4DALDH1A1GAATSHR | |
| SCHEMBL14655577 | 0.73 | PGK1 (0.40) | PDE4BPDE4DALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111957-A | DOPAMINERGIC | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |