SCHEMBL9024006

SCHEMBL9024006

CCNc1ccc(OC)c(O)c1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.43
PDE4D Q08499 1/20 0.43
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
IDO1 P14902 1/20 0.40
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 3/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TUBB4A P04350 4/20 0.38
TUBB P07437 4/20 0.38
TUBA3C P0DPH7 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9023468 0.86 IDO1 (0.42) IDO1MAPTTDP1CYP3A4KDM4E
SCHEMBL9023989 0.83 ALOX5 (0.42) CYP3A4ALDH1A1MAPK1HSD17B10ALOX5
SCHEMBL6380564 0.83 PDE4B (0.43) PDE4BPDE4DMAPTTDP1KDM4E
SCHEMBL9023607 0.83 KDM4E (0.41) MAPTTDP1CYP3A4KDM4EALDH1A1
SCHEMBL9024157 0.79 MAPT (0.42) GABRA1GABRB2MAPTTDP1CYP3A4
SCHEMBL9023765 0.79 AR (0.40) MAPTTDP1CYP3A4LMNATUBB4A
Hydrochloric Acid SCHEMBL9124952 0.78 MAPT (0.41) GABRA1GABRB2MAPTTDP1CYP3A4
SCHEMBL4778825 0.76 PDE4B (0.43) PDE4BPDE4DMAPTTDP1CYP3A4
SCHEMBL7399442 0.75 PDE4B (0.40) PDE4BPDE4DMAPTKDM4EALDH1A1
SCHEMBL11640261 0.75 PDE4B (0.40) PDE4BPDE4DMAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US claimed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP claimed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP disclosed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US disclosed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP disclosed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO disclosed