SCHEMBL11640329

SCHEMBL11640329

N#CCc1ccc(NC(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.65
NPC1 O15118 3/20 0.55
LMNA P02545 2/20 0.55
MAPT P10636 2/20 0.55
HTT P42858 2/20 0.55
RAB9A P51151 3/20 0.51
THRB P10828 1/20 0.51
MEN1 O00255 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 2/20 0.49
SAE1 Q9UBE0 1/20 0.46
UBA2 Q9UBT2 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
POLB P06746 2/20 0.45
MITF O75030 1/20 0.45
USP2 O75604 1/20 0.45
RECQL P46063 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
PKM P14618 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL11640635 0.96 KMT2A (0.61) KMT2ANPC1LMNAMAPTHTT
SCHEMBL549173 0.83 KMT2A (0.63) KMT2ANPC1LMNAMAPTHTT
SCHEMBL5492921 0.83 KMT2A (0.63) KMT2ANPC1LMNAMAPTHTT
SCHEMBL4122896 0.82 RAB9A (0.61) KMT2ANPC1LMNAMAPTHTT
SCHEMBL4119195 0.82 NPC1 (0.61) KMT2ANPC1LMNAMAPTHTT
SCHEMBL11119026 0.81 KMT2A (0.45) KMT2AMEN1ALDH1A1SAE1UBA2
SCHEMBL8185146 0.81 KMT2A (0.74) KMT2ANPC1MAPTRAB9AMEN1
SCHEMBL18952169 0.80 KMT2A (0.59) KMT2ANPC1LMNAMAPTHTT
SCHEMBL8688649 0.80 KMT2A (0.59) KMT2ANPC1LMNAMAPTHTT
SCHEMBL7774502 0.80 KMT2A (0.59) KMT2ANPC1LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2022-04-26 US disclosed
US-20210387954-A1 OXADIAZOLES AS FUNGICIDES PI INDUSTRIES LIMITED (IN) 2021-12-16 US disclosed
EP-3860982-A1 OXADIAZOLES AS FUNGICIDES PI Industries Ltd. (IN) 2021-08-11 EP disclosed
US-20210017100-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE AbbVie Deutschland GmbH & Co. KG (DE) 2021-01-21 US disclosed
US-10836688-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2020-11-17 US disclosed
EP-3408258-B1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE ABBVIE DEUTSCHLAND (DE) 2020-07-01 EP disclosed
US-20200148610-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE ABBVIE INC. 2020-05-14 US disclosed
WO-2020070611-A1 OXADIAZOLES AS FUNGICIDES PI INDUSTRIES LTD (IN) 2020-04-09 WO disclosed
EP-3408258-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE Abbvie Deutschland GmbH & Co. KG (DE) 2018-12-05 EP disclosed
US-20170217850-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE ABBVIE INC. 2017-08-03 US disclosed
WO-2017129796-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE AbbVie Deutschland GmbH & Co. KG (DE) 2017-08-03 WO disclosed
US-4094875-A RODENTICIDES ROHM AND HAAS COMPANY (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017100-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE LIPA, ALG1, CEL KMT2A 4694/4885NPC1 1900/4885LMNA 1270/4885
US-20200148610-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE LIPA, ALG1, CEL KMT2A 4694/4885NPC1 1900/4885LMNA 1270/4885
US-10836688-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose LIPA, ALG1, CEL KMT2A 4694/4885NPC1 1900/4885LMNA 1270/4885
US-20170217850-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE LIPA, ALG1, CEL KMT2A 4694/4885NPC1 1900/4885LMNA 1270/4885
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose LIPA, ALG1, CEL KMT2A 4694/4885NPC1 1900/4885LMNA 1270/4885
US-20210387954-A1 OXADIAZOLES AS FUNGICIDES CYP1B1, CYP1A1, OXA1L KMT2A 1956/4885NPC1 2945/4885LMNA 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.