SCHEMBL11640352

SCHEMBL11640352

CCc1noc2cc(-c3cccnc3)n(C)c(=O)c12

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 2/20 0.56
NR4A2 P43354 3/20 0.54
NPC1 O15118 5/20 0.53
RAB9A P51151 5/20 0.53
CASP3 P42574 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
MITF O75030 1/20 0.48
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11540754 0.87 NPC1 (0.70) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11646682 0.82 NPC1 (0.79) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL6069151 0.81 NR4A2 (0.80) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11539301 0.81 NPC1 (0.54) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11546656 0.81 NPC1 (0.65) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL6069469 0.80 NPC1 (0.79) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11544223 0.80 NPC1 (0.53) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11543626 0.80 NPC1 (0.59) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11640959 0.78 DCTPP1 (0.52) DCTPP1NR4A2NPC1RAB9ACASP3
SCHEMBL11542745 0.78 NR4A2 (0.67) DCTPP1NR4A2NPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124714-A TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS, NEUROLEPTICS, ANTIULCER AGENTS SANDOZ, INC. (US) 1978-11-07 US disclosed
US-4064251-A TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS SANDOZ, INC. (US) 1977-12-20 US disclosed