Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644828 | 0.84 | DCTPP1 (0.66) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11540754 | 0.83 | NPC1 (0.70) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL6069299 | 0.81 | NPC1 (0.75) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11544858 | 0.80 | NPC1 (0.51) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL6069069 | 0.79 | NR4A2 (0.75) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11646737 | 0.79 | NR4A2 (0.65) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11542430 | 0.79 | NPC1 (0.68) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11640352 | 0.78 | DCTPP1 (0.56) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11539301 | 0.78 | NPC1 (0.54) | DCTPP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11640292 | 0.77 | NPC1 (0.65) | DCTPP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124714-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS, NEUROLEPTICS, ANTIULCER AGENTS | SANDOZ, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4064251-A | TRANQUILIZERS, SLEEP INDUCERS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1977-12-20 | — | — | US | disclosed |