Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855562 | 0.73 | LMNA (0.49) | LMNAMAPK1NFKBIARELATDP1 | |
| SCHEMBL8855618 | 0.73 | LMNA (0.54) | LMNAMAPK1NFKBIARELATDP1 | |
| SCHEMBL11863391 | 0.70 | ALDH1A1 (0.42) | LMNAMAPK1NFKBIARELATDP1 | |
| SCHEMBL8947516 | 0.68 | CYP3A4 (0.40) | LMNAMAPK1NFKBIARELATDP1 | |
| SCHEMBL11645840 | 0.67 | LMNA (0.42) | LMNAMAPK1NFKBIARELATDP1 | |
| SCHEMBL8947549 | 0.66 | CYP3A4 (0.43) | LMNAMAPK1TDP1POLBKMT2A | |
| SCHEMBL11644265 | 0.66 | MAPK1 (0.41) | LMNAMAPK1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL11642421 | 0.64 | ALDH1A1 (0.50) | MAPK1TDP1POLBSMN1; SMN2GAA | |
| SCHEMBL8947515 | 0.64 | MAPK1 (0.48) | LMNAMAPK1TDP1KMT2AGAA | |
| SCHEMBL8855540 | 0.64 | PLK1 (0.43) | LMNAMAPK1TDP1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122184-A | Benzimidazole insecticides | ELI LILLY AND COMPANY (US) | 1978-10-24 | — | — | US | disclosed |