Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14911645 | 0.78 | TSHR (0.36) | CYP3A4MAPT | |
| SCHEMBL5154417 | 0.74 | ALDH1A1 (0.40) | TDP1MAPT | |
| SCHEMBL7474882 | 0.72 | — | — | |
| SCHEMBL1230762 | 0.71 | TDP1 (0.41) | TDP1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL4105337 | 0.71 | TDP1 (0.39) | TDP1MAPT | |
| SCHEMBL31108124 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9204488 | 0.69 | TDP1 (0.41) | TDP1MAPT | |
| SCHEMBL18830941 | 0.68 | — | — | |
| SCHEMBL24525700 | 0.67 | ADRA2A (0.36) | MAPT | |
| SCHEMBL2145330 | 0.66 | GPR35 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108867-A | 2-Aminothiophenes | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-22 | — | — | US | disclosed |