Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645955 | 0.79 | CHRM2 (0.35) | CHRM2KMT2ACYP2D6MEN1CHRM1 | |
| SCHEMBL8811351 | 0.75 | KMT2A (0.47) | CHRM2KMT2ACYP2D6MEN1CHRM1 | |
| SCHEMBL11643226 | 0.72 | CHRM2 (0.39) | CHRM2KMT2ACYP2D6MEN1CHRM1 | |
| SCHEMBL24833770 | 0.69 | KMT2A (0.42) | CHRM2KMT2AMEN1CHRM1TSHR | |
| SCHEMBL7675335 | 0.66 | CHRM2 (0.35) | CHRM2KMT2ACYP2D6MEN1CHRM1 | |
| SCHEMBL251451 | 0.64 | TSHR (0.37) | KMT2AMEN1TSHR | |
| SCHEMBL2784910 | 0.64 | NAAA (0.38) | KMT2AMEN1TSHR | |
| SCHEMBL9737052 | 0.64 | CHRM2 (0.37) | CHRM2KMT2ACYP2D6MEN1CHRM1 | |
| SCHEMBL15986943 | 0.64 | TSHR (0.33) | KMT2ATSHR | |
| SCHEMBL17267009 | 0.64 | TSHR (0.33) | CHRM2KMT2AMEN1CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130710-A | POLYOLEFIN STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |