Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19638262 | 0.71 | CYP3A4 (0.36) | CHRM2KMT2ACHRM1MEN1CYP2D6 | |
| SCHEMBL11645955 | 0.69 | CHRM2 (0.35) | CHRM2KMT2ACHRM1MEN1CYP2D6 | |
| SCHEMBL15006305 | 0.69 | GRM6 (0.33) | ALDH1A1 | |
| SCHEMBL727510 | 0.67 | GAA (0.37) | — | |
| Hydrochloric Acid SCHEMBL10565670 | 0.67 | LMNA (0.35) | CYP2D6LMNA | |
| SCHEMBL11661484 | 0.66 | GAA (0.31) | — | |
| SCHEMBL11640591 | 0.66 | CHRM2 (0.33) | CHRM2KMT2ACHRM1MEN1CYP2D6 | |
| SCHEMBL241284 | 0.64 | KMT2A (0.50) | CHRM2KMT2ACHRM1MEN1CYP2D6 | |
| SCHEMBL1285572 | 0.64 | CHRM2 (0.38) | CHRM2KMT2ACHRM1MEN1CYP2D6 | |
| SCHEMBL11195088 | 0.63 | CYP19A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500303-B1 | DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-31 | — | — | US | claimed |