SCHEMBL11643226

SCHEMBL11643226

CC(=O)OC1CC(C)(C)N(C2CCCCC2)C(C)(C)C1OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.39
CHRM1 P11229 4/20 0.39
CHRM4 P08173 3/20 0.39
CHRM3 P20309 3/20 0.39
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KCNH2 Q12809 2/20 0.34
CYP2C9 P11712 1/20 0.34
MTOR P42345 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP3A4 P08684 1/20 0.34
LMNA P02545 1/20 0.33
RAD52 P43351 1/20 0.33
CYP2D6 P10635 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC47A2 Q86VL8 1/20 0.32
SLC47A1 Q96FL8 1/20 0.32
SLC18A3 Q16572 1/20 0.31
ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11645955 0.75 CHRM2 (0.35) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL11640591 0.72 CHRM2 (0.33) CHRM2CHRM1MEN1KMT2ACYP2C19
SCHEMBL3475992 0.67 TSHR (0.35) KMT2A
SCHEMBL16672047 0.66 CHRM2 (0.47) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL27804199 0.66 TSHR (0.32) KMT2A
SCHEMBL7926056 0.64 CHRM2 (0.48) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL7926060 0.64 CHRM2 (0.48) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL7920287 0.64 CHRM2 (0.48) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL7675335 0.63 CHRM2 (0.35) CHRM2CHRM1CHRM4CHRM3MEN1
SCHEMBL8462829 0.61 TSHR (0.49) CHRM2CHRM1CHRM4CHRM3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130710-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1978-12-19 US disclosed