Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642064 | 0.91 | POLB (0.50) | POLBL3MBTL1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL11647190 | 0.88 | GAA (0.42) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11640137 | 0.85 | PTGER4 (0.44) | POLBL3MBTL1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11648352 | 0.84 | RAB9A (0.40) | HTTEPHX1ALDH1A1EPHX2RAB9A | |
| SCHEMBL11645788 | 0.82 | CA1 (0.49) | POLBHTTALDH1A1KDM4EHDAC3 | |
| SCHEMBL11646651 | 0.82 | ALDH1A1 (0.46) | POLBHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11644479 | 0.79 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2EPHX1ALDH1A1EPHX2 | |
| SCHEMBL11642976 | 0.79 | NPC1 (0.48) | POLBSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11638524 | 0.78 | MDM4 (0.43) | L3MBTL1HTTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11642862 | 0.78 | NPC1 (0.52) | POLBL3MBTL1HTTSMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |