Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492895 | 0.88 | CYP17A1 (0.53) | CYP19A1POLBMEN1KMT2AQPCT | |
| SCHEMBL9200864 | 0.86 | CYP19A1 (0.58) | CYP19A1POLBMEN1KMT2AQPCT | |
| SCHEMBL11495476 | 0.85 | POLB (0.49) | CYP19A1POLBMEN1KMT2ANOS1 | |
| SCHEMBL11386867 | 0.81 | CYP11B1 (0.48) | CYP19A1POLBMEN1KMT2ACYP11B1 | |
| SCHEMBL11485554 | 0.78 | HSD11B1 (0.43) | CYP19A1POLBMEN1KMT2AQPCT | |
| SCHEMBL11390051 | 0.78 | TBXAS1 (0.49) | CYP19A1POLBMEN1KMT2ACYP11B1 | |
| SCHEMBL11492996 | 0.76 | KMT2A (0.43) | CYP19A1POLBMEN1KMT2ANOS1 | |
| SCHEMBL11643688 | 0.76 | CYP19A1 (0.56) | CYP19A1POLBQPCTCYP11B1CYP11B2 | |
| SCHEMBL11496380 | 0.76 | CYP11B1 (0.57) | CYP19A1POLBMEN1KMT2ACYP11B1 | |
| SCHEMBL11492756 | 0.75 | CYP11B1 (0.47) | POLBMEN1KMT2AQPCTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123542-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |