Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642218 | 0.93 | LMNA (0.55) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11643317 | 0.92 | LMNA (0.54) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11393959 | 0.91 | LMNA (0.67) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11642713 | 0.89 | ALDH1A1 (0.53) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11648831 | 0.87 | RXFP1 (0.46) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11393962 | 0.87 | RXFP1 (0.54) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11642117 | 0.87 | RXFP1 (0.54) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11639817 | 0.86 | RXFP1 (0.45) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11642302 | 0.86 | LMNA (0.60) | RXFP1LMNAMEN1KMT2AHPGD | |
| SCHEMBL11638740 | 0.86 | ALDH1A1 (0.46) | RXFP1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | claimed |
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |