Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | MYC | P01106 | 1/20 | 0.62 |
| ▸ | MAX | P61244 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289498 | 0.88 | MAPT (1.00) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11646536 | 0.86 | MAPT (0.73) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11646555 | 0.85 | SMN1; SMN2 (0.76) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11616056 | 0.85 | NAMPT (0.74) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL11646017 | 0.83 | KMT2A (0.74) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL16566466 | 0.80 | LMNA (0.77) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11646615 | 0.80 | ALDH1A1 (1.00) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL29258778 | 0.80 | NAMPT (0.81) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL26485834 | 0.80 | LMNA (0.71) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6297654 | 0.79 | CA9 (1.00) | MAPTMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |