Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LSS | P48449 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613865 | 0.83 | NAMPT (0.82) | KMT2ALMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL16566466 | 0.83 | LMNA (0.77) | KMT2ALMNACA9ALDH1A1MAPT | |
| SCHEMBL11642147 | 0.83 | MAPT (0.79) | KMT2AGAALMNACA9ALDH1A1 | |
| SCHEMBL11647675 | 0.82 | ALDH1A1 (0.73) | KMT2AGAALMNACA9ALDH1A1 | |
| SCHEMBL6297654 | 0.82 | CA9 (1.00) | KMT2AGAALMNACA9ALDH1A1 | |
| SCHEMBL11647965 | 0.80 | POLB (0.79) | KMT2AGAALMNACA9ALDH1A1 | |
| SCHEMBL29258807 | 0.79 | NAMPT (0.80) | KMT2AMEN1NAMPT | |
| SCHEMBL14586801 | 0.78 | LMNA (0.64) | KMT2AGAALMNAALDH1A1MAPT | |
| SCHEMBL11647735 | 0.78 | ALDH1A1 (1.00) | KMT2AGAALMNAALDH1A1MAPT | |
| SCHEMBL11644262 | 0.78 | ALDH1A1 (0.71) | KMT2AGAALMNACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |