Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640867 | 0.88 | TDP1 (0.38) | TDP1ALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL11639632 | 0.86 | HDAC8 (0.40) | TDP1ALDH1A1 | |
| SCHEMBL11637355 | 0.83 | TDP1 (0.43) | TDP1NPSR1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL31614348 | 0.76 | TDP1 (0.48) | TDP1NPSR1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11638353 | 0.75 | HDAC8 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11639534 | 0.75 | HDAC8 (0.39) | ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL10696330 | 0.75 | TDP1 (0.52) | TDP1NPSR1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL14541275 | 0.74 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7736363 | 0.74 | L3MBTL1 (0.48) | TDP1L3MBTL1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28154641 | 0.74 | TDP1 (0.35) | TDP1L3MBTL1ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076849-A | AROMATIC SECONDARY AMINES | CANADA PACKERS LIMITED (CA) | 1978-02-28 | — | — | US | disclosed |