Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733710 | 0.89 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL7733717 | 0.81 | L3MBTL1 (0.37) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL31614348 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL11674050 | 0.80 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL4454171 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL9015910 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL6242838 | 0.78 | TDP1 (0.61) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL4621245 | 0.76 | TDP1 (0.58) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL7621627 | 0.75 | GAA (0.42) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL10408246 | 0.75 | MAPT (0.44) | ALDH1A1THRBLMNAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
| US-4480008-A | Solid polymer binders for thermosetting powder coating compositions, powder coating compositions containing these binders and metal objects coated with these coating compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |