Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586641 | 0.93 | NPC1 (0.50) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11640872 | 0.93 | NPC1 (0.50) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11587549 | 0.93 | NPC1 (0.50) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL9289411 | 0.88 | TP53 (0.43) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11583718 | 0.87 | LTA4H (0.43) | NPC1JAK2RAB9APAX8TDP1 | |
| SCHEMBL11637359 | 0.82 | TDP1 (0.42) | NPC1JAK2RAB9APAX8TDP1 | |
| SCHEMBL11638360 | 0.80 | NPC1 (0.45) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11639542 | 0.80 | NPC1 (0.45) | NPC1JAK2RAB9APAX8ESR1 | |
| SCHEMBL2211961 | 0.79 | ALDH1A1 (0.38) | NPC1RAB9ATDP1TP53MEN1 | |
| SCHEMBL1258403 | 0.79 | TSHR (0.42) | TDP1TP53MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1251759-C | Biological degradable injectable bracket of modified hydrogel for use in cartilage tissue engineering | UNIV TSINGHUA (CN) | 2006-04-19 | — | — | CN | claimed |
| CN-1539385-A | Biological degradable injectable bracket of modified hydrogel for use in cartilage tissue engineering | 清华大学 | 2004-10-27 | — | — | CN | claimed |
| CN-1251759-C | Biological degradable injectable bracket of modified hydrogel for use in cartilage tissue engineering | UNIV TSINGHUA (CN) | 2006-04-19 | — | — | CN | disclosed |
| CN-1539385-A | Biological degradable injectable bracket of modified hydrogel for use in cartilage tissue engineering | 清华大学 | 2004-10-27 | — | — | CN | disclosed |
| US-4076849-A | AROMATIC SECONDARY AMINES | CANADA PACKERS LIMITED (CA) | 1978-02-28 | — | — | US | disclosed |