Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635695 | 0.81 | ALDH1A1 (0.55) | KMT2AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6579776 | 0.78 | KMT2A (0.71) | KMT2AKDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL11638788 | 0.77 | MEN1 (0.60) | KMT2AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3427228 | 0.76 | MAPK1 (0.76) | KMT2AKDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL7014724 | 0.74 | RECQL (0.67) | KMT2AKDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL9628928 | 0.74 | KMT2A (0.60) | KMT2AKDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL11638822 | 0.73 | LMNA (0.56) | KMT2AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11638100 | 0.73 | KDM4E (0.43) | KMT2AKDM4EALDH1A1HPGDRECQL | |
| SCHEMBL11369367 | 0.73 | KMT2A (0.68) | KMT2AKDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL11453080 | 0.72 | LMNA (0.65) | KMT2AKDM4EALDH1A1CYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124587-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-11-07 | — | — | US | disclosed |