Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641031 | 0.90 | ADRB2 (0.39) | ADRB2LMNAADRB1HTR1ASLC6A2 | |
| SCHEMBL11639419 | 0.89 | DPP4 (0.32) | ADRB2LMNAADRB1HTR1ASLC6A2 | |
| SCHEMBL10387783 | 0.86 | ADRB1 (0.50) | ADRB2LMNAADRB1HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10388921 | 0.84 | LMNA (0.51) | ADRB2LMNAADRB1HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10388040 | 0.84 | LMNA (0.51) | ADRB2LMNAADRB1HTR1ASLC6A2 | |
| SCHEMBL11644483 | 0.84 | ADRB2 (0.49) | ADRB2SMN1; SMN2GAADPP4XDH | |
| SCHEMBL11029926 | 0.84 | ADRB2 (0.41) | ADRB2ADRB1SLC6A2SLC6A3KDM4E | |
| SCHEMBL11643593 | 0.82 | ADRB2 (0.38) | ADRB2ADRB1TSHRKDM4ECYP3A4 | |
| SCHEMBL11643587 | 0.81 | SMN1; SMN2 (0.33) | ADRB2ALDH1A1POLBTHRBRECQL | |
| SCHEMBL11646153 | 0.79 | DPP4 (0.36) | ADRB2LMNAADRB1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119710-A | ANALGESICS, UTEROSPASMOLYTICS, ANTISPASTICS, BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-10-10 | — | — | US | disclosed |