Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11643959 | 0.99 | ADRB2 (0.60) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL11023770 | 0.82 | ADRB2 (0.61) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL11026851 | 0.82 | ADRB1 (0.61) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL10882011 | 0.81 | ADRB1 (0.60) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL11036484 | 0.81 | ADRB2 (0.60) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL11642474 | 0.81 | LMNA (0.58) | ADRB2ADRB1TSHRHIF1AADRA1A | |
| SCHEMBL10658170 | 0.79 | ADRB2 (0.64) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL10879505 | 0.78 | ADRB2 (0.62) | ADRB2ADRB1ADRB3TSHRHIF1A | |
| SCHEMBL11647977 | 0.78 | KDM4E (0.42) | ADRB2ADRB1ADRB3KMT2AKDM4E | |
| SCHEMBL11028356 | 0.77 | ADRB2 (0.43) | ADRB2ADRB1ADRB3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119710-A | ANALGESICS, UTEROSPASMOLYTICS, ANTISPASTICS, BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-10-10 | — | — | US | disclosed |