SCHEMBL8462829

SCHEMBL8462829

CC(=O)OC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 1/20 0.47
ESR1 P03372 1/20 0.47
HSD17B10 Q99714 1/20 0.47
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
EPHX1 P07099 2/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
CHRM2 P08172 4/20 0.31
CHRM4 P08173 4/20 0.31
CHRM1 P11229 4/20 0.31
CHRM3 P20309 4/20 0.31
CHRM5 P08912 2/20 0.31
NAAA Q02083 1/20 0.31
HTT P42858 2/20 0.31
SLC18A3 Q16572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067197 0.89 TSHR (0.38) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL9270235 0.88 TSHR (0.38) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL9270239 0.88 TSHR (0.38) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL3473600 0.85 TSHR (0.39) TSHRKMT2AALDH1A1ESR1HSD17B10
Hydrochloric Acid SCHEMBL9337013 0.84 TSHR (0.35) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL580975 0.84 NAAA (0.45) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL13412654 0.84 CYP2C19 (0.40) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL13474861 0.84 TSHR (0.35) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL9334232 0.84 TSHR (0.35) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL8944559 0.84 EPHX1 (0.41) TSHRKMT2AALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312908-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2022-04-26 US disclosed
US-10465117-B2 Liquid-crystalline medium, method for the stabilization thereof, and liquid-crystal display MERCK PATENT GMBH (DE) 2019-11-05 US disclosed
US-20180163134-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
US-20180163134-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
EP-3327103-A1 LIQUID CRYSTAL MEDIUM, METHOD FOR THE STABILISATION THEREOF AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2018-05-30 EP disclosed
EP-3327102-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2018-05-30 EP disclosed
US-9920248-B2 Compounds and liquid-crystalline medium MERCK PATENT GMBH (DE) 2018-03-20 US disclosed
US-9920248-B2 Compounds and liquid-crystalline medium MERCK PATENT GMBH (DE) 2018-03-20 US disclosed
EP-2514800-B2 Compounds and liquid crystalline medium MERCK PATENT GMBH (DE) 2018-03-07 EP disclosed
EP-2722380-B1 Liquid crystal medium, method for the stabilisation thereof and liquid crystal display MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-2514800-A2 Compounds and liquid crystalline medium Merck Patent GmbH (DE) 2012-10-24 EP disclosed
EP-0634449-B1 Polyether with sterically hindered amine side chains as stabilizing agents CIBA GEIGY AG (CH) 1999-09-01 EP disclosed
US-5719257-A OBTAINED BY ANIONIC POLYMERIZATION OF DERIVATIVES OF 2,2,6,6-TETRAMETHYL-4-/2,3-EPOXYPROPOXY/PIPERIDINE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-02-17 US disclosed
US-5665885-A FOR STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING INFLUENCE OF LIGHT, OXYGEN AND/OR HEAT CIBA-GEIGY CORPORATION (US) 1997-09-09 US disclosed
US-5637714-A OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5616637-A PHOTOSTABILITY; OXIDTION AND HEAT RESISTANT CIBA-GEIGY CORPORATION (US) 1997-04-01 US disclosed
US-5521282-A FROM 4-/2,3-EPOXYPROPOXY/-2,2,6,6-TETRAMETHYLPIPERIDINE CIBA-GEIGY CORPORATION (US) 1996-05-28 US disclosed
US-5457204-A For polymers CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
EP-0634399-A1 Adducts of hindered amine-epoxides as stabilisers CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed
EP-0634449-A2 Polyether with sterically hindered amine side chains as stabilizing agents CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed