Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562422 | 0.78 | LMNA (0.42) | ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL29464296 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL22055454 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL11644979 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL11641020 | 0.65 | ALDH1A1 (0.51) | ALDH1A1GAALMNAMEN1TSHR | |
| SCHEMBL9580270 | 0.63 | ALDH1A1 (0.44) | ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL1585949 | 0.61 | — | — | |
| SCHEMBL10392936 | 0.61 | MB (0.33) | — | |
| SCHEMBL9613932 | 0.59 | NQO2 (0.41) | ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL11440681 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113860-A | O-alkyl-O-[4-alkylpyrimidin(2)yl]-(thiono)-(thiol) phosphoric (phosphonic) acid esters and insecticidal, acaricidal and nematocidal compositions containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |