Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22055454 | 1.00 | LMNA (0.37) | LMNANQO2 | |
| SCHEMBL562422 | 0.86 | LMNA (0.42) | LMNANQO2 | |
| SCHEMBL11644979 | 0.79 | LMNA (0.37) | LMNANQO2 | |
| SCHEMBL14967319 | 0.79 | LMNA (0.37) | LMNANQO2 | |
| SCHEMBL14438127 | 0.75 | LMNA (0.34) | LMNA | |
| SCHEMBL2396549 | 0.75 | LMNA (0.44) | LMNA | |
| SCHEMBL1258640 | 0.72 | — | — | |
| SCHEMBL8642157 | 0.72 | — | — | |
| SCHEMBL11507948 | 0.72 | MB (0.31) | — | |
| SCHEMBL11641020 | 0.72 | ALDH1A1 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272303-B | Pyrimidine five-membered nitrogen heterocyclic derivative, preparation method and medical application thereof | 上海拓界生物医药科技有限公司 | 2024-09-17 | — | — | CN | disclosed |
| US-20220073521-A1 | PYRIMIDINE AND FIVE-MEMBERED NITROGEN HETEROCYCLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | TUOJIE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073521-A1 | PYRIMIDINE AND FIVE-MEMBERED NITROGEN HETEROCYCLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | PTPN5, PTPN11, PTPN1 | LMNA 4801/4885NQO2 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.