Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639989 | 0.82 | NAAA (0.43) | MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL27529498 | 0.79 | POLB (0.46) | POLBBRD4ATMALOX15GAA | |
| SCHEMBL11056858 | 0.79 | POLB (0.46) | POLBBRD4ATMALOX15GAA | |
| SCHEMBL1311126 | 0.79 | MEN1 (0.33) | ATMGAAKMT2AL3MBTL1MEN1 | |
| SCHEMBL1434672 | 0.77 | POLB (0.40) | POLBATMALOX15GAAMGAM | |
| SCHEMBL372547 | 0.76 | — | — | |
| SCHEMBL17635968 | 0.76 | POLB (0.42) | POLBBRD4ATMALOX15GAA | |
| SCHEMBL11642236 | 0.75 | ALDH1A1 (0.46) | KMT2AL3MBTL1ALDH1A1LMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL20447769 | 0.74 | ALOX15 (0.42) | POLBATMALOX15GAAMGAM | |
| SCHEMBL22441532 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118368-A | DERIVATIVES OF 2,6-DIMETHYL-2,6-DIALKYL-4-AMINO-4-CARBOXYLATE-PIPERIDINES | SANKYO COMPANY LIMITED (JP) | 1978-10-03 | — | — | US | claimed |
| US-4118368-A | DERIVATIVES OF 2,6-DIMETHYL-2,6-DIALKYL-4-AMINO-4-CARBOXYLATE-PIPERIDINES | SANKYO COMPANY LIMITED (JP) | 1978-10-03 | — | — | US | disclosed |