Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641093 | 0.90 | CDC7 (0.40) | UTS2RDRD2HRH3MLNRNR1I2 | |
| SCHEMBL11648471 | 0.88 | PARP1 (0.35) | DRD2CHRM2DRD3CDC7L3MBTL1 | |
| SCHEMBL11643564 | 0.86 | CDC7 (0.32) | HRH3CHRM2CHRM1CHRM3HRH1 | |
| SCHEMBL11730098 | 0.85 | ALOX12 (0.33) | UTS2RDRD2HRH3MLNRNR1I2 | |
| SCHEMBL11642674 | 0.80 | MAPKAPK2 (0.37) | UTS2RCHRM2CHRM1CHRM3HRH1 | |
| SCHEMBL11645863 | 0.80 | CHRM2 (0.42) | HRH3CHRM2ADRA2AOPRM1SIGMAR1 | |
| SCHEMBL11643919 | 0.79 | KDM4E (0.44) | CDC7 | |
| SCHEMBL11645136 | 0.79 | CHRM2 (0.44) | HRH3CHRM2ADRA2AHRH1L3MBTL1 | |
| SCHEMBL11642301 | 0.78 | CDC7 (0.39) | DRD2CHRM2CDC7SIGMAR1NPSR1 | |
| SCHEMBL11643574 | 0.77 | DRD2 (0.39) | UTS2RDRD2HRH3MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118494-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |