Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644851 | 0.86 | CYP1A1 (0.66) | MAOBTNKSPARP1TNKS2KDM4E | |
| SCHEMBL11647508 | 0.84 | TNKS (0.60) | TNKSKDM4EMAPTPAX8ABCG2 | |
| SCHEMBL11643881 | 0.84 | MAOB (0.63) | MAOBTNKSKDM4EMAPTPAX8 | |
| SCHEMBL11647907 | 0.84 | PAX8 (0.51) | KDM4EMAPTPAX8ABCG2HPGD | |
| SCHEMBL11645163 | 0.84 | GABRP (0.60) | MAOBTNKSPARP1TNKS2KDM4E | |
| SCHEMBL1740996 | 0.83 | ABCG2 (0.71) | MAOBTNKSKDM4EMAPTABCG2 | |
| SCHEMBL28031347 | 0.83 | ABCG2 (0.48) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL11645915 | 0.83 | TNKS (0.63) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL12278322 | 0.83 | MAOB (0.62) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL24368454 | 0.83 | NISCH (0.51) | TNKSKDM4EMAPTPAX8ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3974144-A | BENZOFURAN, BENZOTHIOPHENE, NAPHTHOFURAN, OPTICAL BRIGHTENER | STERLING DRUG INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |