Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TNKS | O95271 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116289 | 0.83 | ABCG2 (1.00) | ABCG2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11645802 | 0.83 | MAOB (0.60) | ABCG2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11644851 | 0.82 | CYP1A1 (0.66) | ABCG2MAPTKDM4EALDH1A1MAOB | |
| SCHEMBL1742227 | 0.81 | CYP1A1 (0.73) | ABCG2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11647508 | 0.80 | TNKS (0.60) | ABCG2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL11643881 | 0.80 | MAOB (0.63) | ABCG2MAPTKDM4EALDH1A1MAOB | |
| SCHEMBL11645163 | 0.80 | GABRP (0.60) | ABCG2MAPTKDM4EMAOBRAB9A | |
| SCHEMBL11647907 | 0.80 | PAX8 (0.51) | ABCG2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL3685028 | 0.80 | MAOB (0.63) | ABCG2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11645915 | 0.79 | TNKS (0.63) | ABCG2MAPTKDM4EALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | claimed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | disclosed |